Talk:Stamina/@comment-112.36.195.91-20190110174218/@comment-39326604-20190504093617

Altered Metabolism has it's own article, which explains how it works.

Basically yes, it's high Toxicity that triggers it, above 50% to be exact.

Willow works very well with this talent due to it's high toxicity and because it grants immunity to Stun and Knockdown, so basically you become immune to Poison, Pain, Stun and Knockdown when both are active.