Talk:Madness mutagen/@comment-128.106.128.142-20180629092049/@comment-93.105.250.220-20180703213149

Actually it has to be monsters that drop Basic Mutagens as Madness counts as a Basic Mutagen. So Nekkers don't drop them as they only drop Lesser.

I heard of someone getting a Madness Mutagen from the Crazed Nekkers you meet at the beginning of In the Claws of Madness, but even if that is true you can't farm them.

However all Endrega except for the queen drop Basic Mutagens so you can farm them for Madness.

Also I'm not sure but difficulty appears to influence drop rate. While I was playing Dark Mode I managed to farm 7 Madness Mutagens in just 2 hours, while on Hard Mode it was indeed average 1 per hour. It could be dumb luck, but even after I was done with farming them I still got 5 more as random drops during the rest of the game.