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Depletion is a level 1 Glyphword in the Hearts of Stone expansion that can be crafted by the Runewright.

Crafting Requirements

Glyphs, Runestones, and Enchantments in The Witcher 3: Wild Hunt

Base game	Lesser Glyph of Aard Glyph of Aard Greater Glyph of Aard Lesser Glyph of Axii Glyph of Axii Greater Glyph of Axii Lesser Glyph of Igni Glyph of Igni Greater Glyph of Igni Lesser Glyph of Quen Glyph of Quen Greater Glyph of Quen Lesser Glyph of Yrden Glyph of Yrden Greater Glyph of Yrden

Hearts of Stone	Lesser Glyph of Binding Glyph of Binding Greater Glyph of Binding Lesser Glyph of Mending Glyph of Mending Greater Glyph of Mending Lesser Glyph of Reinforcement Glyph of Reinforcement Greater Glyph of Reinforcement Lesser Glyph of Warding Glyph of Warding Greater Glyph of Warding

Base game	Lesser Chernobog runestone Chernobog runestone Greater Chernobog runestone Lesser Dazhbog runestone Dazhbog runestone Greater Dazhbog runestone Lesser Devana runestone Devana runestone Greater Devana runestone Lesser Morana runestone Morana runestone Greater Morana runestone Lesser Perun runestone Perun runestone Greater Perun runestone Lesser Stribog runestone Stribog runestone Greater Stribog runestone Lesser Svarog runestone Svarog runestone Greater Svarog runestone Lesser Triglav runestone Triglav runestone Greater Triglav runestone Lesser Veles runestone Veles runestone Greater Veles runestone Lesser Zoria runestone Zoria runestone Greater Zoria runestone

Hearts of Stone	Pyerog runestone Tvarog runestone

Enchantments (only with HOS)

Runewords	Preservation Dumplings Placation Rejuvenation Elation Severance Replenishment Invigoration Prolongation

Glyphwords	Deflection Heft Depletion Usurpation Ignition Rotation Entanglement Beguilement Protection Balance Retribution Levity Possession Eruption

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