Ekhidna mutagen is an alchemy ingredient in The Witcher 3: Wild Hunt that is used to craft ekhidna decoction. Like all special mutagens, they can only be dropped by their corresponding creature. They act like lesser blue mutagens when placed in the diamond-shaped slots in the character panel.
Melusine will always drop this mutagen during Contract: Here Comes the Groom. It is hard to obtain without facing her, as ekhidnae prefer water over land, and monsters killed in water rarely drop anything. However, there are a few locations where it's possible to farm ekhidnae like in the western parts of An Skellig, near the secondary quest The Tower Outta Nowheres.
Notes[]
- In an undocumented change for Patch 1.08, all mutagen icons were changed. However, there was still a bug for those on Steam and Origin that didn't reflect this and was later fixed in Patch 1.22. Despite this, some may still see the original icons instead, even with a fully patched game.