Iron ore is a crafting component in The Witcher 2: Assassins of Kings, and The Witcher 3: Wild Hunt.
The Witcher 2: Assassins of Kings 
Edit
Iron ore is a crafting component which is quite easily found. It is required for most swords, even silver swords as a pure silver sword would not be hard enough to be of use. The ore is also used in several items:
The Witcher 3: Wild Hunt Edit
Iron ore is a crafting component that is needed to craft the following items:
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