Lesser blue mutagen is an alchemy ingredient and is be used to craft Blue mutagens. They can also be used to augment abilities, but are not as effective as their regular or greater counterparts. When placed in the diamond-shaped slot in the character panel, they give +5% to sign intensity, which increases by 5 up to a max of +20% if all 3 skills attached to it are blue.

Blood and Wine expansion

With Blood and Wine, the player can now craft these with other ingredients.

Crafting Requirements Tw2 icon crafting.svg
Crafting Requirements Tw2 icon crafting.svg


  • In an undocumented change for Patch 1.08, all mutagen icons were changed. However, there was still a bug for those on Steam and Origin that didn't reflect this and was later fixed in Patch 1.22. Despite this, some may still see the original icons instead, even with a fully patched game.
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