For The Witcher 3: Wild Hunt, the English voice actors were directed by Kate Saxon, with additional directing by Mark Healy and Damien Goodwin. The Polish voice actors were directed by Konrad Tomaszkiewicz and Michal Konarski. For voice actors in the first expansion, see Hearts of Stone voice actors, and for their colleagues in the second expansion, see Blood and Wine voice actors.
- Doug Cockle as Geralt of Rivia
- Charles Dance as Emhyr var Emreis
- Jo Wyatt as Ciri
- Denise Gough as Yennefer
- Jaimi Barbakoff as Triss Merigold
- Katie McGuinness as Keira Metz
- Pandora Colin as Philippa Eilhart
- Michael Maloney as Avallac'h
- Steven Hartley as Eredin
- Andrew Greenough as Ge'els
- James Clyde as Phillip Strenger
- William Roberts as Vesemir
- Christian Contreras as Lambert
- Tom Clarke Hill as Eskel
- Mark Lewis Jones as Letho
- John Schwab as Dandelion
- Emma Hiddleston as Priscilla
- Alexander Morton as Zoltan Chivay
- Richard Hawley as Sigismund Dijkstra
- Mark Healy as Vernon Roche
- Nico Lennon as Radovid V
- Sarah Greene as Cerys an Craite
- Allen Leech as Hjalmar an Craite
- Gary Lilburn as Crach an Craite
- Patrick Drury as Ermion
- Geoffrey Breton as Morvran Voorhis
- Peter Marinker as Thaler / The Pellar
- Ewan Bailey as Dudu / Cyprian Wiley / Vimme Vivaldi
- Laura Rogers as Fringilla Vigo / Ves / Tamara Strenger
- Julian Mere as Caesar Bilzen / Ogg, Pogg and Rogg
- Timothy Watson as Éibhear Hattori
- Alec Newman as Graden
- Eleanor Tremain as Brewess, Weavess, and Whispess